NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2 DELETION ATTENUATES POLYHEXAMETHYLENE GUANIDINE-INDUCED LUNG INJURY IN MICE

Nicotinamide adenine dinucleotide phosphate oxidase 2 deletion attenuates polyhexamethylene guanidine-induced lung injury in mice

Inhalation of polyhexamethylene guanidine phosphate (PHMG) can cause pulmonary fibrosis.Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are enzymes that produce reactive oxygen species, which may be involved in tissue damage in various lung diseases.To investigate whether the Nox2 isoform of Nox is involved in the progression of

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Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.

INTRODUCTION: Microvesicles (MVs), earlier referred to as microparticles, represent a major type of extracellular vesicles currently considered as novel biomarkers in various clinical settings such as autoimmune disorders.However, the analysis of MVs in body fluids has not been fully standardized yet, and there are numerous pitfalls that hinder the

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